Is "Entourage" HBO's New Signature Show?

Sure, since "Sex and the City" and "Six Feet Under" are Gone, "The Sopranos" and "Curb Your Enthusiasm" are wheezing to their finish lines, "Deadwood" and "Rome" have been cancelled and "Big Love" is on the bubble. I'll admit, the series has little bite but its amiable charm has grown on me once I realized it wasn't terribly insider-y. (A fact borne out painfully by the episode surrounding the opening weekend of "Aquaman.") And it's not a signature show, but how could this article mention virtually every series on HBO and NOT mention "The Wire," which begins a new season in a few days and has received the biggest advance raves for any show in years?